Table 3.
Analgesic activity by acetic-acid-induced writhing and tail flick methods.
| Treatment | Dose (mg/kg) | Writhing reflex (Reaction time in sec) | % Inhibition | Tail flick (Reaction time in sec) | % Inhibition |
|---|---|---|---|---|---|
| Control | 15.00 ± 0.40 | 0 | 22.22 ± 0.56 | 0 | |
| Paracetamol | 50 | 3 ± 0.365* | 80 | — | — |
| Morphine | 5 | — | — | 5.20 ± 0.10* | 76.59 |
| S. robusta aqueous extract | 200 | 5.5 ± 0.763* | 63.33 | 7.68 ± 0.27* | 65.43 |
| 400 | 4.33 ± 0.421* | 71.13 | 6.6 ± 0.15* | 70.29 | |
| S. robusta methanol extract | 200 | 6 ± 0.516* | 60.00 | 8.14 ± 0.51* | 63.36 |
| 400 | 5 ± 0.365* | 66.66 | 7.46 ± 1.00* | 66.42 |
Results are expressed as mean ± SEM (n = 6), *P <0.001 compared to control (2% aqueous Tween 80 v/v).