Table 2. Patient characteristics associated with Streptococcus pneumoniae serotype 5 invasive pneumococcal disease, northern Alberta, Canada, 2005–2009*.

Characteristic	Adjusted odds ratio (95% CI)	p value
Demographic
Age group, y
<16	0
16–65	2.10 (1.14–3.89)	0.018
>65	1.09 (0.48–2.47)	0.846
Male sex	1.13 (0.82–1.56)	0.443
First Nations heritage	2.34 (1.53–3.57)	<0.001
Homeless	1.83 (1.07–3.12)	0.026
Substance abuse
Tobacco	1.90 (1.29–2.81)	0.001
Alcoholism	1.19 (0.82–1.75)	0.363
Illicit drug	1.89 (1.31–2.73)	0.001
Concurrent condition
Cancer within 5 y before IPD	0.32 (0.14–0.71)	0.005
Central nervous system disorder†	0.83 (0.52–1.33)	0.445
Cardiovascular disease‡	0.51 (0.32–0.82)	0.006
Hematologic abnormality§	0.19 (0.06–0.55)	0.002
Diabetes mellitus	0.60 (0.32–1.12)	0.109
Cirrhosis	0.18 (0.06–0.50)	0.001
Chronic renal failure¶	0.34 (0.08–1.55)	0.155
Rheumatoid arthritis	0.40 (0.09–1.84)	0.239
Mental problem#	0.64 (0.41–0.99)	0.045
Musculoskeletal impairment**	0.72 (0.44–1.18)	0.191
Chronic obstructive pulmonary disease	1.19 (0.71–2.00)	0.516

*IPD, invasive pneumococcal disease. Adjusted odds ratios were obtained by multivariable logistic regression analysis.
†Chronic central nervous system leak, epilepsy or other seizure disorder, Parkinsonism or other neurodegenerative disorder, Alzheimer or other dementia, or stroke or other neurologic disease.
‡Congestive heart failure, coronary artery disease, myocardial infarction, arrhythmia, congenital defect, atrial fibrillation, hypertension, or other.
§Sickle cell anemia, other anemia, bleeding disorder/coagulopathy, or other.
¶Nephritic syndrome or other.
#Depression or other.
**Osteoarthritis, osteoporosis, or other.