Table 2. Parameters in chronic HEV infections among SOT recipients, the Netherlands, 2000–2011*.
Parameter | Median | Range | ULN (F/M) |
---|---|---|---|
Peak alanine aminotransferase, U/L | 301 | 81–909 | 30/40 |
Peak aspartate aminotransferase, U/L | 172 | 66–1016 | 30/36 |
Peak gamma-glutamil transferase, U/L | 299 | 72–1740 | 34/49 |
Peak bilirubin, μmol/L | 16 | 5–100 | 16/16 |
Peak HEV RNA, cycle threshold values | 20.0 | 16.7–26.6 | NA |
Period of HEV RNA positivity, mo | 16 | 6–55 | NA |
Time between SOT and first HEV RNA–positive result, mo | 2.0 | –0.3 to 20.1 | NA |
Time of HEV RNA positivity before HEV IgM positive, d | 32 | 0–826 | NA |
Time of HEV RNA positivity before HEV IgG positive, d | 124 | 0–826 | NA |
*HEV, hepatitis E virus; SOT, solid organ transplant; ULN (F/M), upper limit of normal (female/male); NA, not applicable.