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. 2012 Jun;28(6):594–606. doi: 10.1089/aid.2011.0271

Table 2.

Virus Isolation Rates for Plasma Samples as a Function of Fiebig Stages or Viral Load

Fiebig stage Pos Total % Pos Viral load Pos Total % Pos
I 2 27 7.4% <1,000 0 20 0.0%
II/III 8 11 72.7% 1,000–10,000 1 14 7.1%
IV 2 7 28.6% 10,000–100,000 10 21 47.6%
V 9 15 60.0% 100,000–1,000,000 15 20 75.0%
VI 9 20 45.0% >1,000,000 4 5 80.0%
Total 30 80 37.5% Total 30 80 37.5%

Most efficient virus isolation was observed for plasma samples at Fiebig stages II and V, although virus could be isolated at each stage. Efficiency of virus isolation went up as viral load increased. Virus isolation was not achieved for samples with viral loads below 1000 copies/ml.