Table 1. Protocol for CH and REC.
Day | FiO2 (%) | Microarray | Biomarker |
NX-0 | 21 | • | • |
CH-1 | 15 | • | |
CH-2 | 13 | ||
CH-3 | 12 | • | |
CH-4 | 11 | ||
CH-5 | 10 | ||
CH-6 | 9 | ||
CH-7 | 8 | • | |
CH-8 | 10 | ||
CH-9 | 9 | ||
CH-10 | 9 | ||
CH-11 | 9 | ||
CH-12 | 8 | ||
CH-13 | 8 | ||
CH-14 | 8 | • | • |
REC-1 | 21 | ||
REC- 2 | 21 | ||
REC-3 | 21 | ||
REC-4 | 21 | ||
REC-5 | 21 | ||
REC-6 | 21 | ||
REC-7 | 21 | • | |
REC-8 | 21 | ||
REC-9 | 21 | ||
REC-10 | 21 | ||
REC-11 | 21 | ||
REC-12 | 21 | ||
REC-13 | 21 | ||
REC-14 | 21 | • | • |
Protocol used for Microarray profile (Protocol 1) and Biomarker (Protocol 2) experiments. The • indicates the peripheral blood harvest from 5 different animals. The fraction of inspiration (FiO2) was changed every 24 hours.