Table 1. Comparison of sham-operated wild-type and EphA4 knockout spinal cords: gene ontology groups over-represented in list of differentially expressed genes.
Biological Process | p-value | Molecular Function | p-value |
Regulation of pH | 0.0058 | Enzyme activator activity | 0.0021 |
Monovalent inorganic cation | GTPase activator activity | 0.0201 | |
Homeostasis | 0.0089 | GTPase regulator activity | 0.0392 |
Mitochondrion organization | 0.0145 | Nucleoside-triphosphatase regulator | |
Regulation of transcription | 0.0317 | Activity | 0.0419 |
Transcription | 0.0346 | ||
Regulation of cell morphogenesis | Cellular Component | p-value | |
Involved in differentiation | 0.0361 | Nucleus | 0.0083 |
Regulation of gene expression | 0.0375 | Intracellular organelle | 0.0143 |
Cellular macromolecule biosynthetic | Organelle | 0.0145 | |
Process | 0.0408 | Cell junction | 0.0175 |
Macromolecule biosynthetic process | 0.0420 | Intracellular membrane-bounded | |
Positive regulation of apoptosis | 0.0442 | Organelle | 0.0275 |
Positive regulation of programmed | Membrane-bounded organelle | 0.028 | |
cell death | 0.0456 | Synapse | 0.0362 |
Positive regulation of cell death | 0.0463 | Proteasome complex | 0.0423 |
(GoMiner analysis: significance level of p<0.05).