Skip to main content
. 2012 May 22;7(5):e37623. doi: 10.1371/journal.pone.0037623

Figure 3. The biodistribution of I-131 uptake in the mouse bladder of hybrid spectral CLT.

Figure 3

An athymic nude mouse received the intravenous tail injection of 400 µCi I-131. Fig. 3(A) is the single luminescent image of the mouse 2 h after the injection which was acquired without using filters; this is depicted in pseudo-color superimposed on the corresponding photograph. The luminescent image of the mouse using the 700–40 nm filter is shown in Fig. 3(B) where there is almost no optical signal when using the other filters including 580–40 nm, 620–40 nm, and 660–40 nm. Fig. 3(C) is the 3D radiopharmaceutical I-131 biodistribution rendering of hybrid spectral CLT. Fig. 3(D) and (E) are the reconstruction results in horizontal, coronal, and sagittal views of the hybrid spectral CLT and the single-spectral CLT based on the 700–40 nm spectrum.