Table 2. Demographic profiles and clinical characteristics of CAP and HCAP patients with and without concomitant pulmonary tuberculosisa.
| Overall patient, n = 1635 | P value | CAP patients, n = 934 | P value | HCAP patients, n = 701 | P value | ||||
| With TB, n = 46 | Without TB, n = 1589 | With TB, n = 25 | Without TB, n = 909 | With TB, n = 21 | Without TB, n = 680 | ||||
| Mean age (SD) | 76.2 (15.3) | 72.7 (15.7) | 0.14 | 74.1 (16.8) | 72.5 (16.6) | 0.65 | 79.6 (13.4) | 72.9 (14.5) | 0.034 |
| Male gender | 38 (82.6%) | 1134 (71.4%) | 0.10 | 22 (88%) | 652 (71.7%) | 0.07 | 16 (76.2%) | 482 (70.9%) | 0.60 |
| Smoking habit | 20 (43.5%) | 583 (36.7%) | 0.35 | 12 (48%) | 317 (34.9%) | 0.18 | 8 (38.1%) | 266 (39.1%) | 0.93 |
| Previous anti-TB treatment | 9 (19.6%) | 73 (4.6%) | <0.001 | 4 (16%) | 45 (5%) | 0.015 | 5 (23.8%) | 28 (4.1%) | <0.001 |
| Comorbidities | |||||||||
| Malignancy | 14 (30.4%) | 308 (19.4%) | 0.06 | 5 (20%) | 74 (8.1%) | 0.036 | 9 (42.9%) | 234 (34.4%) | 0.42 |
| Renal insufficiency | 6 (13%) | 193 (12.1%) | 0.85 | 3 (12%) | 66 (7.3%) | 0.37 | 3 (14.3%) | 127 (18.7%) | 0.61 |
| Chronic liver disease | 1 (2.2%) | 85 (5.3%) | 0.34 | 1 (4%) | 40 (4.4%) | 0.92 | 0 | 45 (6.6%) | 0.39 |
| Diabetes | 14 (30.4%) | 429 (27%) | 0.61 | 8 (32%) | 227 (25%) | 0.42 | 6 (28.6%) | 202 (29.7%) | 0.91 |
| COPD | 11 (23.9%) | 239 (15%) | 0.10 | 7 (28%) | 147 (16.2%) | 0.12 | 4 (19%) | 92 (13.5%) | 0.47 |
| Pneumonia severity | |||||||||
| PSI score (SD) | 149.9 (35.7) | 132.8 (34.4) | 0.001 | 140.3 (36.1) | 126.1 (31.5) | 0.033 | 161.3 (32.5) | 141.7 (36.0) | 0.017 |
| CURB65 score (SD) | 1.91 (1.05) | 1.81 (1.08) | 0.60 | 1.80 (1.00) | 1.77 (1.05) | 1.00 | 2.05 (1.12) | 1.87 (1.10) | 0.46 |
| Chest film presentation | |||||||||
| Upper lung involvement | 19 (41.3%) | 642 (40.4%) | 0.90 | 8 (32%) | 331 (36.4%) | 0.65 | 11 (52.4%) | 311 (45.7%) | 0.55 |
| Bilateral lung involvement | 24 (52.2%) | 679 (42.7%) | 0.20 | 12 (48%) | 366 (40.3%) | 0.44 | 12 (57.1%) | 313 (46%) | 0.31 |
| Type of pneumonia | 0.73 | - | - | ||||||
| CAP | 25 (54.3%) | 905 (57%) | - | - | - | - | |||
| HCAP | 21 (45.7%) | 684 (43%) | - | - | - | - | |||
| TB testing on admission | 25 (54.3%) | 537 (33.8%) | 0.004 | 16 (64%) | 359 (39.5%) | 0.014 | 9 (42.9%) | 178 (26.2%) | 0.089 |
a
The data are presented as n (%) unless otherwise stated.
HCAP, healthcare-associated pneumonia; CAP, community acquired pneumonia; TB, tuberculosis; SD, standard deviation; COPD, chronic obstructive pulmonary disease; PSI, pneumonia severity index; CURB65, confusion, urea, respiratory rate, blood pressure, age 65.