Table 5. Impact of concomitant tuberculosis in treatment outcome of HCAP and CAP patientsa.
| CAP patients, n = 934 | P value | HCAP patients, n = 701 | P value | |||
| With TB, n = 25 | Without TB, n = 909 | With TB, n = 21 | Without TB, n = 680 | |||
| Organs dysfunction within 48 hours | ||||||
| Respiratory failure | 3 (12%) | 115 (12.7%) | 0.92 | 10 (47.6%) | 154 (22.6%) | 0.008 |
| Septic shock | 4 (16%) | 91 (10%) | 0.33 | 5 (23.8%) | 135 (19.9%) | 0.66 |
| Altered mental status | 4 (16%) | 66 (7.3%) | 0.10 | 6 (28.6%) | 145 (21.3%) | 0.43 |
| Renal dysfunction | 2 (8%) | 67 (7.4%) | 0.91 | 1 (4.8%) | 104 (15.3%) | 0.18 |
| Liver dysfunction | 0 | 1 (0.1%) | 1.00 | 0 | 3 (0.4%) | 0.76 |
| Coagulopathy | 0 | 6 (0.7%) | 1.00 | 1 (4.8%) | 13 (1.9%) | 0.36 |
| Thrombocytopenia | 2 (8%) | 26 (2.9%) | 0.14 | 1 (4.8%) | 50 (7.4%) | 0.65 |
| ICU admission | 11 (44%) | 179 (19.7%) | 0.003 | 13 (61.9%) | 243 (35.7%) | 0.014 |
| Length of hospital stay (SD) | ||||||
| All patients | 32.0 (27.4) | 19.0 (20.3) | 0.002 | 39.6 (34.1) | 23.7 (27.0) | 0.009 |
| Survivors | 24.5 (17.9) | 18.4 (19.7) | 0.19 | 46.2 (42.6) | 23.1 (23.9) | 0.002 |
| Non-survivors | 56.1 (39.3) | 23.4 (24.4) | 0.003 | 32.4 (21.4) | 25.7 (34.6) | 0.54 |
| 28 days hospital free day (SD) | 7.2 (8.9) | 11.9 (8.8) | 0.008 | 4.2 (7.5) | 7.8 (8.5) | 0.039 |
| Mean Numbers of antibiotics used (SD) | 1.74 (0.69) | 1.61 (0.75) | 0.41 | 1.29 (0.46) | 1.37 (0.62) | 0.52 |
| Long-term ventilator dependent | 1 (4%) | 18 (2%) | 0.48 | 1 (4.8%) | 32 (4.7%) | 0.99 |
| Mortality | ||||||
| 30-day mortality | 2 (8%) | 73 (8%) | 1.00 | 4 (19%) | 133 (19.6%) | 0.95 |
| 60-day mortality | 3 (12%) | 99 (10.9%) | 0.86 | 7 (33.3%) | 166 (24.4%) | 0.35 |
| In-hospital mortality | 6 (24%) | 106 (11.7%) | 0.06 | 10 (47.6%) | 179 (26.3%) | 0.030 |
a
The data are presented as n (%)unless otherwise stated.
HCAP, healthcare-associated pneumonia; CAP, community acquired pneumonia; TB, tuberculosis; SD, standard deviation; ICU, intensive care unit.