Levels of mineralocorticoid receptor (MR) following restraint stress in Control (Ctrl), Sham, and fluid percussion injured (FPI) rats at post-injury day (PID) (A) 1 and (B) 7. Effects on MR of dexamethasone (DEX) at a high (0.1 mg/kg) and low (0.01 mg/kg) dose are indicated. DEX or saline (Sal) were administered 2 hr prior to 30-min restraint. Each value represents the mean ± SEM of 6-9 rats per group. * P<0.05, **P<0.005, ***P<0.0005 compared to Control under the corresponding drug condition and PID.+++P<0.0005, compared to Sham under the corresponding drug condition and PID.