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. Author manuscript; available in PMC: 2013 May 17.
Published in final edited form as: Neuroscience. 2012 Mar 15;210:296–307. doi: 10.1016/j.neuroscience.2012.03.006

Figure 6.

Figure 6

Correlation analysis: spared tissues and lesion volume versus BBB scores. Regression plots for final mean BBB scores versus (A) spared gray matter (GM), (B) spared white matter (WM), tissue sparing at injury epicenter (C) and lesion volume (D). Significant positive correlations were found between final BBB scores and spared gray matter (p<0.005), white matter (p<0.0001) and spared tissue at epicenter (p<0.005), while total injured tissue volume showed a significant negative correlation with final BBB scores (p<0.0001). Notably, encircled symbols illustrate that increased tissue sparing with ALC treatment was significantly correlated with higher BBB scores, compared to vehicle treatment.