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. Author manuscript; available in PMC: 2013 Jul 2.
Published in final edited form as: Neuroimage. 2012 Apr 5;61(3):525–532. doi: 10.1016/j.neuroimage.2012.03.083

Table 2. Parameters for all regions with linear or piecewise linear fits.

For individual ROIs (i.e., excluding whole hemispheres), the average age of breakpoint for the piecewise linear regression models for AD offspring is 58.1 (+/−3.3) years, the average annual change before breakpoint = 0.0 mm/year, and the average annual change after breakpoint = −0.018 (+/−0.0093) mm/year.

ROI AD offspring Non-AD offspring
Annual
change
before
breakpoint
(mm/year)		 Breakpoint
(age, year)		 Annual
change
after
breakpoint
(mm/year)		 Annual
change
before
breakpoint
(mm/year)		 Breakpoint
(age, year)		 Annual
change
after
breakpoint
(mm/year)
All LH regions 0.0 55.9 −0.015 NS
All RH regions 0.0 58.6 −0.016 NS
LH precuneus 0.0 56.5 −0.013 NS
LH superior frontal gyrus 0.0 58.4 −0.015 NS
RH lateral parietal 0.0 60.3 −0.024 NS
RH inferior frontal gyrus 0.0 54.4 −0.012 NS
RH superior frontal gyrus 0.0 56.1 −0.016 0.0 (linear)
RH lingual-parahippocampal gyrus 0.0 64.4 −0.037 0.0 66.0 −0.024
RH precuneus 0.0 56.6 −0.011 NS