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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: J Immunol. 2012 Apr 20;188(11):5257–5266. doi: 10.4049/jimmunol.1101934

Figure 1. The frequency of B cell progenitors in BM is reduced following acute SCI.

Figure 1

Representative FACS gating strategy to identify B cell subsets in the BM at day 8 (A) and day 28 (B) after T3-SCI, T9-SCI, T3-Lam, T9-Lam or in un-injured control mice. Contour plots show the mean frequency and standard deviation of B220+AA4.1+ Developing B cells in the BM (left panels) and further subsetting of IgM+CD19+ immature (IMM) and IgM−CD19+ Pro/Pre B cell populations (right panels) among live singlets. At day 8 post-SCI, n=5 for un-injured, n=8 for T9-Lam, n=6 for T9-SCI, n=8 for T3-Lam, and n=5 for T3-SCI. At day 28 post-SCI, n=5 for uninjured, n=7 for T9-Lam, n=5 for T9-SCI, n=7 for T3-Lam, and n=6 for T3-SCI.