Table II.
Total Cells | TR1 | TR2 | TR3 | FO | MZ | ||
---|---|---|---|---|---|---|---|
Un-injuredb | 131.6±26.2 | 2.7±0.6 | 2.5±0.8 | 2.3±0.7 | 28.9±5.4 | 3.2±0.5 | |
Day 8 Post Injuryc | T9-Lam | 138.0±9.2 | 0.9±0.1* | 1.3±0.2* | 1.2±0.2* | 24.1±3.0 | 2.9±0.6 |
T9-SCI | 104.3±15.6*,# | 0.6±0.2* | 0.9±0.2* | 1.0±0.3* | 18.3±2.1* | 2.3±0.5 | |
T3-Lam | 111.1±22.1 | 1.5±0.9* | 1.6±0.7* | 1.6±0.5 | 21.2±6.5* | 3.1±1.9 | |
T3-SCI | 111.3±18.5 | 0.3±0.1*,# | 0.7±0.2*,# | 0.7±0.2*,# | 20.2±3.9* | 2.5±0.5 | |
Day 28 Post Injuryd | T9-Lam | 149.7±32.9 | 3.8±0.8* | 2.6±0.4 | 2.2±0.4 | 30.4±8.2 | 3.2±0.7 |
T9-SCI | 86.8±12.5*,# | 2.5±0.6# | 2.2±0.6 | 2.0±0.7 | 21.1±4.0# | 3.4±0.4 | |
T3-Lam | 119±22.2 | 3.5±0.7 | 2.5±0.5 | 2.0±0.4 | 22.9±4.6 | 2.9±0.5 | |
T3-SCI | 93.6±24.1* | 1.6±0.4*,# | 1.8±0.5 | 1.8±1.0 | 22.3±5.9 | 4.3±1.3*,# |
Number ± SD of cells (×106) per spleen, representative FACS plots shown in Fig. 2. Figures shown are representative of 3 experiments at each post-injury time point. Data shown has been pooled across 2 experiments for un-injured controls, 1 for laminectomies, and 1 for SCI at each level.
n=10 for Un-injured
n=8 for T9-Lam, n=6 for T9-SCI, n=8 for T3-Lam, and n=5 for T3, SCI.
n=7 for T9-Lam, n=5 for T9-SCI, n=7 for T3-Lam, and n=6 for T3-SCI.
Denotes significant difference from un-injured control at p<0.05
Denotes significant difference from respective laminectomy control at p<0.05