Table II.

A2AAR−/− hematopoietic cells produce more severe EAE while A2AAR−/− recipient mice are more resistant to EAE development.^A

	IncidenceB	Mean Dayof OnsetC	Mean Max EAE ScoreD
WTinto WT	7/7	7.7+/−0.4	3.0+/−0.2
A2AAR−/−into WT	8/8	8.0+/−0.4	3.9+/−0.4
WT into A2AAR−/−	7/7	9.6+/−1.6	1.1+/−0.4

^ABone marrow chimeric mice were induced to develop EAE and scored daily for EAE severity based on the 5 point scale assessing ascending paralysis.

^BIndicates the number of mice that achieved a score of 0.5 (weak tail) in the experimental group.

^CIndicates the average day of onset (an EAE score of 0.5, +/− the s.e.m.).

^DIndicated the average of the maximum EAE score for each individual mouse (+/− the s.e.m.).

^EWT into WT compared to A2AAR−/− into WT Mean Max EAE Score; p = 0.0566.

^FWT into WT compared to WT into A2AAR−/− Mean Max EAE Score; p = 0.00073.