TS - Turner Syndrome; POI – Primary Ovarian Insufficiency; US – United States adult population of women; IBD – Inflammatory Bowel Disease; CD-Celiac Disease.
^For TS the numbers of diagnoses are actual count; For POI and US female population the numbers represent expected diagnoses for a sample equal to TS group, i.e. 224. For the POI group the counts are extrapolated from the actual diagnoses in 457 individual. For the general US population of women the numbers were derived from published epidemiological data, based on 30 relatively common autoimmune diseases, including 22 found in our study populations (see text) and adjusted for a sample of 224 patients. **P <0.0001 for comparisons TS v POI and TS v US population; *P <0.0001 for comparison of POI v US population. ( 2 test with Yates correction)