Table 3.
Control (40) | TS (49) | P | |
---|---|---|---|
Age (yr) | 34±8 | 31±12 | 0.12 |
Body mass (kg/m2) | 25.8±6.5 | 28.2±8.9 | 0.17 |
TGF β1 (ng/ml) | 11.9±1.3 | 31.6±2.5 | <0.0001 |
TGF β2 (pg/ml) | 1607±71 | 486±80 | <0.0001 |
IL6 (pg/ml) | 5.6±0.2 | 10.3±0.9 | 0.0004 |
IL10 (pg/ml) | 4.9±0.3 | 3.5±0.1 | <0.0001 |
Control group included 20 women with POI and 20 female volunteers with normal ovarian function. Cytokine levels were equal for POI and normal volunteer groups (shown in Fig. 2) so here the data were combined as ‘Controls’. Cytokine levels were compared by ANCOVA with age and BMI as covariates.