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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: J Autoimmun. 2012 Feb 18;38(4):315–321. doi: 10.1016/j.jaut.2012.01.015

Table 3.

Disruption of cytokine balance in women with TS

Control (40) TS (49) P
Age (yr) 34±8 31±12 0.12
Body mass (kg/m2) 25.8±6.5 28.2±8.9 0.17
TGF β1 (ng/ml) 11.9±1.3 31.6±2.5 <0.0001
TGF β2 (pg/ml) 1607±71 486±80 <0.0001
IL6 (pg/ml) 5.6±0.2 10.3±0.9 0.0004
IL10 (pg/ml) 4.9±0.3 3.5±0.1 <0.0001

Control group included 20 women with POI and 20 female volunteers with normal ovarian function. Cytokine levels were equal for POI and normal volunteer groups (shown in Fig. 2) so here the data were combined as ‘Controls’. Cytokine levels were compared by ANCOVA with age and BMI as covariates.