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. Author manuscript; available in PMC: 2013 May 21.
Published in final edited form as: Chem Res Toxicol. 2012 May 1;25(5):993–1003. doi: 10.1021/tx200463s

Table 3.

Relative amounts of 1,3-[3H2]-B[a]P-7,8-dione metabolites and adduct in three human lung cells at 24h.

Metabolites and adduct Metabolite A549 H358 HBEC-KT
GSH-B[a]P-7,8-dione M1 0.7 % 0.8 %
O-mono-sulfate-catechol M2 12.2 % 14.9 % 3.5 %
O-mono-glucuronide-catechol M3 4.3 %
NAC-B[a]P-7,8-dione M4 1.4 % 2.4 % 11.1 %
Unknown metabolite with m/z 444 M5 16.2 % 25.3 % 6.4 %
adenine-B[a]P-7,8-dione M6 30.1 % 25.7 % 48.4 %
B[a]P-7,8-dione 5.7 % 4.2 % 2.1 %
Mono-hydroxylated-B[a]P-7,8-dione M7 7.8 % 1.7 % 10.1 %
O-methylated-catechol M8 6.6 % 1.2 % 5.8 %
Other unknown metabolites 15.0 % 23.8 % 12.6 %