Table 2.

Percent differences in selected features of the daily cortisol curve associated with a 1 standard deviation increase in inflammatory marker

	Interleukin-6 pg/mL		Interleukin-10 pg/mL		TNF-α pg/mL
	% Differences	Confidence Intervals	% Differences	Confidence Intervals	% Differences	Confidence Intervals
Sociodemographic controls
Wakeup level	-1.7	[-4.7, 1.1]	-2.2	[-6.0, 1.7]	-2.5*	[-4.6, -0.5]
CAR	-3.3*	[-6.3, -0.4]	-0.5	[-3.5, 2.4]	0.9	[-1.9, 3.8]
% decline/hour	0.5**	[0.2, 0.9]	0.2+	[-0.02, 0.4]	0.3*	[0.01, 0.5]
Behavioral Controls
Wakeup level	-1.6	[-4.7, 1.3]	-2.3	[-6.2, 1.5]	-2.7**	[-4.7, -0.7]
CAR	-3.7*	[-6.7, -0.7]	-0.4	[-3.4, 2.5]	0.7	[-2.2, 3.6]
% decline/hour	0.5**	[0.2, 0.8]	0.2+	[-0.02, 0.4]	0.3*	[0.0, 0.5]
Other Inflammatory Risk Factors
Wakeup level	0.0	[-2.9, 2.8]	-2.2	[-6.0, 1.5]	-2.5**	[-4.4, -0.7]
CAR	-3.3*	[-6.4, -0.2]	-0.3	[-3.2, 2.7]	0.7	[-2.1, 3.5]
% decline/hour	0.4*	[0.1, 0.7]	0.2+	[-0.03, 0.4]	0.3+	[0.0, 0.5]

Note: Demographic controls include: age, gender, race, waketime, study site, cynical-hostility, non-steroidal anti-inflammatory medications, and socioeconomic status. Behavioral controls include: smoking status and physical activity. Inflammatory risk factors include: diabetes, hypertension, and body mass index.

⁺p < .10;

^*p < .05;

^**p < .01.