HMDMs were incubated with EAL or LAL, pre-incubated or not with C1q, at a 5:1 ratio for 1 h. HMDMs were then cultured in HL-1 for 3 h in absence of LPS (A) or in presence of EAL or LAL conditioned media (B). Changes in type I IFNs, IL-27 and IL-10 were determined by qRT-PCR. Results represent means ± s.d. (n = 3 different donors), two-way ANOVA, ** p < 0.01 and *** p < 0.001.