Table 2.
Selected haematological parameters used for characteristics of the studied groups
| Parameter | mHD |
P value mHD1 vs. mHD2 |
HV as controls | |
|---|---|---|---|---|
| mHD1 | mHD2 | |||
| RBC (1012/l) | 3.25 ± 0.47*** | 3.11 ± 0.42*** | 0.03 | 4.6 ± 0.8 |
| HCT (%) | 33.3 ± 318*** | 32.31 ± 3.9*** | 0.64 | 44.3 ± 7.2 |
| HGB (g/dl) | 10.62 ± 1.54*** | 10.5 ± 1.21*** | 0.76 | 14.9 ± 2.0 |
| MCH (pg) | 32.86 ± 4.79 | 34.16 ± 3.7 | 0.15 | 34.2 ± 3.7 |
| MCV (fL) | 98.68 ± 5.86*** | 98.91 ± 5.72*** | 0.81 | 104.6 ± 11.1 |
| TIBC (μmol/l) | 37.66 ± 5.27*** | 42.4.8 ± 8.47*** | 0.0001 | 59.6 ± 5.3 |
| UIBC (μmol/l) | 21.92 ± 8.04*** | 17.942 ± 8.2*** | 0.0021 | 36.4 ± 3.1 |
| Fe (μmol/l) | 15.73 ± 6.68*** | 15.06 ± 7.86*** | 0.63 | 22.7 ± 9.1 |
| sFn (ng/ml) | 1749.55 ± 179.98*** | 1804.72 ± 1086.53*** | 0.88 | 188.2 ± 10.6 |
| TSAT (%) | 42.6 ± 18.95*** | 37.84.8 ± 24.7*** | 0.21 | 38.4 ± 6.5 |
Subjects were divided into patients treated with maintenance haemodialysis (mHD1—at the beginning of the study, mHD2—after 1 year of the study) and healthy volunteers (HV) as controls
The differences between mHD1 and mHD2 were estimated by paired t test. To compare mHD1 and mHD2 with HV as controls, unpaired the Student’s t test for normally distributed variables and the Mann–Whitney rank sum test for the variables with non-normal distribution were used
Data were given are means ± SD
mHD1 patients treated with maintenance haemodialysis at the beginning of the study, mHD2 patients treated with maintenance haemodialysis after 1 year of the study, RBC red blood cells, HCT haematocrit, HGB haemoglobin, MCH mean haemoglobin concentration, MCV mean corpuscular volume, TIBC total iron-binding capacity, UIBC unsaturated iron-binding capacity, Fe serum iron, sFn serum ferritin, TSAT transferrin saturation
Significant differences when P < 0.05
*** P < 0.001 versus HV