Table 2.

Summary BMI statistics for SNPs that were individually associated with BMI

Gene	SNP	Typed	Modelled	MA	MAF	Median (IQR) of BMI per genotype			Effect
						mm*	mM*	MM*
FTO	rs17817449	977	952	G	0.37	18.5 (16.9–20.7)	18.7 (17.2–21.1)	19.1 (17.6–22.5)	1.9
LEP	rs10954174	973	948	A	0.13	18.8 (17.1–21.3)	18.4 (17.2–20.5)	17.4 (16.8–19.1)	−4.0
LEP	rs6966536	972	948	G	0.14	18.6 (17.1–20.8)	18.9 (17.1–21.5)	19.2 (18.5–21.6)	2.9
MC4R	rs17782313	969	945	C	0.25	18.9 (17.4–21.2)	18.5 (17.0–20.9)	19.0 (16.5–20.6)	−1.8

Effect sizes are from individual models, estimated individual percentage change in BMI for each minor allele, independent of age, sex and sex-specific pubertal stage. Effect sizes correspond to p values (adjusted) in table 1.

^*m denotes major allele; M is minor allele.

BMI, body mass index; MA, minor allele; MAF, minor allele frequency; SNP, single nucleotide polymorphism.