Table 1.

DAVID bioinformatics resources sorting of genes for each of the phenotypic classes

GO process term	Enriched genes	p1 value	Bonferroni p value2	fold change
Synaptic Apposition (61 genes)
1 proteasome	17 out of 61 (27.9%)	0.00000	0.00000	22
2 mitotic spindle organization	14 out of 62 (23%)	0.00000	0.00000	8
3 chaperone	5 out of 61 (8.2%)	0.00410	0.25000	7.2
NMJ undergrowth (49 genes)
1 spindle organization	10 out of 49 (20.4%)	0.00002	0.01000	6
NMJ overgrowth (16 genes)
1 cell differentiation	8 out of 16 (50%)	0.00007	0.02000	5.3
Synaptic retractions (60 genes)
1 proteasome	6 out of 60 (10%)	0.00012	0.04500	8.5
2 mitotic spindle organization	8 out of 60 (13.3%)	0.00094	0.46000	4.7
3 Ribosome	4 out of 60 (6.7%)	0.00970	0.15000	7.9
Axonal transport (30 genes)
1 cytoskeletal part	6 out of 30 (20.0%)	0.00410	0.45000	5

¹The p value represents the confidence with which we can conclude that the GO term is overrepresented in each of the phenotypic class compared to the collection of the screened genes.

²The p value is derived from a binomial distribution and the Bonferroni p value results from multiplying this p value by the number of tests performed.