Table 4.

Brain areas^a activated by noxious heat stimulation of ventrum of the right forearm in controls, with maximum activation intensity (1-sample t-scores; cluster-level p < 0.0001) and location of maxima within those areas. Clusters of activation spanned more than one listed area.

Area	Maximum activation intensity group t- score	Talairach co-ordinates RAI (mm) of maxima	Area	Maximum activation intensity group t- score	Talairach co-ordinates RAI (mm) of maxima
L S1	10.1	55, 16, 28	R S1	6.1	−54, 20, 35
L S2	6.9	43, 14, 16	R S2	8.5	−52, 22, 23
L Insula	8.3	35, −17, −6	R Insula	9.6	−32, −25, 2
L medial PPC	8.5	24, 59, 30	R medial PPC	7.6	−5, 65, 51
L SMA/BA6	7.4	4, 22, 62	R SMA/BA6	7.4	−9, 8, 59
L premotor	12.1	27, 14, 53	R premotor	9.2	−19, 11, 57
L Cingulate	6.5	4, −14, 29	R Cingulate	5.9	−11, 4, 35
L IPL	7.7	35, 39, 51	R IPL	6.0	−62, 38, 28
L Ant. STG/BA 38	7.2	47, −7, −7	R Ant. STG/BA 38	6.8	−40, −21, −30
L Amygdala	4.5	19, 8, −15	R Amygdala	-	-
L Parahipp. Gyrus	6	23, 13, −22	R Parahipp. Gyrus	6.9	−28, 31, −15
L MD Thalamus	11.1	8, 20, 4	R MD Thalamus	6.6	−7, 23, 8
L VPL Thalamus	7.7	16, 17, 4	R Pulvinar	6.4	−18, 24, 4
L Caudate	7.2	17, −20, −1	R Caudate	6.6	−19, −17, 8
LPutamen	9.1	19, −8, −7	R Putamen	6.3	−20, −15, 1
L Cerebellum	9.1	11, 46, −16	R Cerebellum	8.6	−25, 59, −24
DMPFC	6	4, −46, 23	Brainstem	7.5	−3, 31, −32

^aL S1 = Left hemisphere S1; R S1 = Right Hemisphere S1; PPC = posterior parietal cortex; SMA = supplementary motor area; BA = Brodmann Area; IPL = inferior parietal lobule; Ant. STG = Anterior Superior Temporal Gyrus; Parahipp. = Parahippocampal; Sup. Front. = Superior Frontal; DMPFC = dorsomedial prefrontal cortex; MD = medial dorsal; VPL = ventroposteriolateral; RAI = Right-Left, Anterior-Posterior, Inferior-Superior.