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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: J Immunother. 2012 Jun;35(5):430–439. doi: 10.1097/CJI.0b013e31825898e8

Figure 6. NFAT.hIL12 transduced young TIL retain the ability to produce IL-12 and IFN-γ after REP.

Figure 6

The transduced CD8 enriched TILs were re-stimulated following the rapid expansion protocol on day 13 (REP2, R2). The activity of the expanded cells was measure two-week later by co-culture with antigen-positive and HLA-A2+ tumor lines: mel526, mel624, and HLA-A2- tumor lines: mel888 and mel938. The level of IL-12 (A) and IFN-γ (B) in the culture was measured by ELISA (shown are the mean values of triplicate determinations, +/− standard deviation).