Table 1. Baseline (week −1) demographic and clinical characteristics.a.
Characteristic | Total N=50 | Placebo N=25 | Gabapentin N=25 | p-value |
---|---|---|---|---|
Demographics | ||||
Age, years | 33.9 (9.7) | 34.4 (10.8) | 33.4 (8.5) | 0.72 |
Male | 44 (88%) | 21 (84%) | 23 (92%) | 0.39 |
White, non-Hispanic | 38 (76%) | 19 (76%) | 19 (76%) | 0.76 |
Education, years | 14 (1.9) | 14.2 (1.9) | 13.6 (1.8) | 0.35 |
College degree | 14 (28%) | 8 (32%) | 6 (24%) | 0.61 |
Full-time employed | 31 (62%) | 13 (52%) | 18 (72%) | 0.36 |
Married | 20 (40%) | 10 (40%) | 10 (40%) | 0.86 |
Clinical assessments | ||||
BDI-II (range 0–63) | 8.8 (5.1) | 9.6 (5.7) | 8.0 (4.5) | 0.29 |
PSQI total score (range 0–21) | 5.9 (3.1) | 5.7 (3.1) | 6.0 (3.1) | 0.48 |
MWC total score (range 0–84) | 14.2 (8.1) | 13.6 (8.3) | 14.8 (7.8) | 0.61 |
MWC craving score (range 0–3) | 2.0 (0.8) | 1.9 (0.8) | 2.1 (0.7) | 0.44 |
MPS total score (range 0–38) | 10.4 (5.9) | 10.5 (6.6) | 10.3 (5.2) | 0.88 |
Body mass index | 27.4 (4.9) | 26.6 (4.5) | 28.1 (5.3) | 0.27 |
Cannabis history | ||||
MJ grams/weekb | 11.0 (18.5) | 9.0 (10.3) | 13.0 (24.1) | 0.46 |
Urinary CN-THCCOOH | 684 (599) | 687 (371) | 682 (771) | 0.98 |
Days of MJ abstinence prior to randomization | 0.9 (0.2) | 1.0 (20) | 0.9 (28) | 0.58 |
Years daily MJ smoking | 11.6 (8.0) | 11.7 (8.5) | 11.5 (7.6) | 0.94 |
Age at first MJ use | 14.5 (3.5) | 15.2 (2.6) | 13.8 (4.1) | 0.14 |
Dollars spent/week on MJb | 86.5 (73.0) | 77.1 (48.0) | 96.0 (91.5) | 0.37 |
Work days missed due to MJb | 2.6 (14.1) | 1.0 (3.0) | 4.1 (19.8) | 0.45 |
Other substance history | ||||
Cigarette smoker | 12 (24%) | 7 (28%) | 5 (20%) | 0.81 |
Parental substance abuse | 20 (40%) | 9 (36%) | 11 (44%) | 0.39 |
Abbreviations: MJ, marijuana; BDI-II, Beck Depression Inventory-II; PSQI, Pittsburgh Sleep Quality Index; MWC, Marijuana Withdrawal Checklist; MPS, Marijuana Problems Scale; CN-THCCOOH, THCCOOH to creatinine ratio.
Values given are mean (SD) unless otherwise specified as number (%).
90 days prior to baseline.