Table 3.
Primary and secondary outcomes
| Outcome | Online Hemodiafiltration | Low-Flux Hemodialysis | HR (95% CI)a | ||
|---|---|---|---|---|---|
| Number of Events | Person-Years of Follow-Up | Number of Events | Person-Years of Follow-Up | ||
| Primary outcome | |||||
| all-cause mortality | 131 | 1085 | 138 | 1085 | 0.95 (0.75–1.20) |
| Main secondary outcomes | |||||
| fatal and nonfatal cardiovascular events | 116 | 916 | 112 | 964 | 1.07 (0.83–1.39) |
| cardiovascular mortality | 37 | 1085 | 46 | 1085 | 0.80 (0.52–1.24) |
| nonfatal cardiovascular disease (first event) | 94 | 915 | 87 | 964 | 1.12 (0.83–1.49) |
| fatal and nonfatal CHD (MI, PTCA, CABG) | 38 | 1000 | 47 | 1022 | 0.81 (0.52–1.23) |
| fatal and nonfatal stroke | 19 | 1066 | 16 | 1062 | 1.17 (0.60–2.27) |
| amputation | 21 | 1058 | 16 | 1068 | 1.31 (0.68–2.51) |
| sudden death | 21 | 1085 | 21 | 1085 | 1.00 (0.55–1.83) |
| vascular intervention | 59 | 978 | 49 | 1010 | 1.23 (0.84–1.79) |
| transplantation | 78 | 800 | 73 | 798 | 1.06 (0.77–1.46) |
| hospital admissions due to infection | 130 | 800 | 110 | 798 | 1.21 (0.94–1.56) |
CHD, coronary heart disease; MI, myocardial infarction; PTCA, percutaneous transluminal coronary angioplasty; CABG, coronary artery bypass graft.
a
Obtained through unadjusted Cox proportional hazards models.