Fig. 1.

Landmarks, Distances, Angles and Parcellation Results. Image A: landmarks used to investigate the shape of the skull and the parenchyma. Landmark A: most posterior point of the superior edge of the AC; Landmark B: central point of the inferior edge of the PC; 1: Glabella* (most anterior point of the frontal bone); 2: Maximum occipital point (most posterior point of the occipital bone); 3: Vertex* (highest point of the cranial vault); 4: Opisthion* (mid-sagittal point on the posterior margin of the foramen magnum); 5: Basion* (mid-sagittal point on the anterior margin of the foramen magnum); 6: most superior point of the dorsum sellae; 7: superior edge of the protuberance occipitalis. Measurements included the occipito-frontal diameter (1 to 2), the vertical calvarial diameter (3 to 4); α: angle of the posterior cranial fossa; β: the clivus angle. Image B: landmarks used to investigate the position and shape of the Talairach landmarks. Landmark C: most anterior inferior point of the genu of the CC projected on the AC-PC line; 8: most anterior point of the genu of the CC (Landmark D); 9: highest most anterior point of the body of the CC; 10: inferior tip of the splenium of the corpus callosum (landmark E); 11: the most inferior point of the anterior cranial fossa projected on the mid-sagittal slice. Measurements made included the length of the CC (C to 10); the diameter of the precentral parcel (8 to A), the central parcel (A to B); the distance AC-PC line (through A and B) to 6 to 4 and to 3; as well as the angle(measuring the opening of the posterior CC (δ); the CC angle (ε) and the angle of the anterior cranial fossa (γ). Landmarks A, B, and C (bright blue) as defined by Talairach and Tournoux (Talairach J, 1988). Image C shows 3D models of the frontal region (blue) and the superior ICC (yellow), which where significantly enlarged in preterm infants. Also displayed is an axial SPGR slide with the outlined parcellated regions superimposed.

* as described in Swennen et al.(Swennen et al., 2006).