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The representative hematoxylin 6 eosin photomicrographs of two types of intraepithelial neoplasia, as precursor lesions to invasive colon carcinoma: low grade (A and B, LGIN) with a basal lining of almost normal nuclei and very few mitotic figures, high grade (C and D, HGIN) with atypical nuclei coming up to the cell apex with many mitotic figures (circle) (all H&E stains, in A and C: 40x, in B and D: 400x magnification).
