FIGURE 1.
Circulating tumor cells (CTCs) isolated from the peripheral blood of a patient suffering from an adenocarcinoma of the lung stained with an antibody against thymidylate synthase (TS). A, Strongly TS expressing CTC which resembles a proliferating CTC in prophase of mitosis and displays chromosome maturation with condensed chromosomes. B, Weakly TS expressing CTC. C, Strongly TS expressing CTC. Magnification 1:1000 (using an oil immersion objective). The shown immunomagnetic beads have a diameter of 4.5 μm.