Table 4.
Laboratory characteristics of 586 pediatric patients with CKD
| Variablea | NHANES Estimates Adjusted to CKiD | CKiD Overall | CKiD GFR Categories, ml/min per 1.73 m2 |
Pb | |||
|---|---|---|---|---|---|---|---|
| ≥50 (n = 211) | ≥40 to <50 (n = 131) | ≥30 to <40 (n = 137) | <30 (n = 107) | ||||
| Sodium, mEq/L | 141.2 | 139.0 | 140.0 | 140.0 | 139.0 | 139.0 | 0.28 |
| Potassium, mEq/L | 4.1 | 4.5 | 4.4 | 4.5 | 4.5 | 4.8 | <0.01 |
| Chloride, mEq/L | 104.3 | 106.0 | 105.0 | 106.0 | 106.0 | 107.0 | <0.01 |
| CO2, mEq/Lc | 26.7 | 22.0 | 24.0 | 22.0 | 22.0 | 21.0 | <0.01 |
| Glucose, mg/dl | 87.3 | 92.0 | 93.0 | 90.0 | 91.0 | 93.0 | 0.73 |
| Calcium, mg/dl | 9.5 | 9.7 | 9.7 | 9.7 | 9.6 | 9.6 | 0.01 |
| Phosphate, mg/dl | 4.2 | 4.5 | 4.4 | 4.4 | 4.6 | 5.0 | <0.01 |
| Albumin, g/dl | 4.4 | 4.3 | 4.3 | 4.3 | 4.3 | 4.2 | <0.01 |
| BUN, mg/dl | 10.9 | 27.0 | 20.0 | 28.0 | 33.0 | 44.0 | <0.01 |
| Creatinine, mg/dl | 0.9 | 1.3 | 0.9 | 1.2 | 1.6 | 2.0 | <0.01 |
| Cystatin C, mg/L | 0.9 | 1.8 | 1.4 | 1.7 | 2.0 | 2.6 | <0.01 |
| Urine protein:creatinine | – | 0.5 | 0.2 | 0.4 | 0.7 | 1.0 | <0.01 |
| Hemoglobin, g/dl | 13.3 | 12.5 | 13.1 | 12.7 | 12.2 | 11.6 | <0.01 |
| Hematocrit, % | 39.4 | 36.8 | 38.5 | 37.4 | 35.2 | 33.7 | <0.01 |
| RCDW, M/mm3 | 12.5 | 13.2 | 13.0 | 13.1 | 13.3 | 13.5 | <0.01 |
| White blood cell, k/mm3 | 7.0 | 6.5 | 6.5 | 6.8 | 6.4 | 6.3 | 0.92 |
| Platelet, k/mm3 | 304 | 280 | 283 | 281 | 283 | 270 | 0.32 |
| Ferritin, ng/dld | 35 | 48 | 44 | 48 | 65 | 58 | 0.02 |
| Serum iron, μg/dld | 86 | 76 | 81 | 74 | 75 | 76 | 0.64 |
| Transferrin saturation, % leveld | 24 | 25 | 25 | 24 | 26 | 26 | 0.20 |
Median values are presented. CKD, chronic kidney disease; NHANES, National Health and Nutrition Examination Survey; CKiD, Chronic Kidney Disease in Children study; CO2, carbon dioxide; BUN, blood urea nitrogen. RCDW, red cell distribution width.
Missing data: n = 5 missing sodium; n = 15 missing potassium; n = 5 missing chloride; n = 5 missing CO2; n = 5 missing glucose; n = 5 missing calcium; n = 14 missing phosphate; n = 5 missing albumin; n = 2 missing serum creatinine; n = 152 missing cystatin C; n = 11 missing hemoglobin; n = 12 missing hematocrit; n = 38 missing RCDW; n = 15 missing white blood cell; n = 12 missing platelet; n = 87 missing ferritin; n = 89 missing serum iron; n = 91 missing transferrin saturation.
P values for trend determined using nonparametric Cuzick test for continuous variables.
On the basis of locally measured values of CO2.
Baseline data defined as first available.