Table 1.
Patient characteristics at enrollment
| Characteristics | Sevelamer (n = 30) | Calcium acetate (n = 29) |
|---|---|---|
| Sex (male/female) | 15/15 | 14/15 |
| Age (years) | 59.6 ± 16.9 | 62.8 ± 14.1 |
| Diabetics | 43% | 41% |
| Time on HD (months) | 30 ± 10 | 28 ± 11 |
| Calcium (mg/dl) | 9.0 ± 0.7 | 9.0 ± 0.5 |
| Phosphate (mg/dl) | 5.4 ± 1.0 | 5.1 ± 0.6 |
| Ca x P (mg2/dl2) | 49.9 ± 13.0 | 46.5 ± 6.4 |
| Intact PTH (pg/ml) | 247 ± 92 | 258 ± 145 |
| C-reactive protein (mg/L) | 6.9 (5 to 9.8) | 5.9 (4.7 to 6) |
| TNF-α (pg/ml) | 8 (6 to 8.4) | 6.4 (5.8 to 8.7) |
| Interleukin-1 (pg/ml) | 0.8 (0.5 to 1.2) | 1.2 (0.8 to 1.4) |
| Interleukin-6 (pg/ml) | 5 (3 to 9.1) | 4.9 (4 to 8.1) |
| Interleukin-10 (pg/ml) | 75 (52 to 98) | 77 (71 to 94) |
| Interleukin-18 (pg/ml) | 599 (514 to 635) | 526 (420 to 621) |
| Endotoxin (EU/ml) | 0.58 (0.51 to 0.60) | 0.60 (0.51 to 0.63) |
| Soluble CD14 (μg/ml) | 2.94 (1.76 to 5.29) | 2.88 (2.35 to 4.70) |
Values represent the mean ± the SDs, or the median and interquartile ranges in parentheses. HD, hemodialysis, PTH, parathyroid hormone.