Table 1.
Demographics and clinical characteristics on day of initial renal replacement therapy
| Parameter | All Patients (n = 1124) |
|---|---|
| Age (years) | 59.7 ± 15.3 |
| Male | 793 (71) |
| Race/ethnicity | |
| Caucasian | 835 (74) |
| African American | 179 (16) |
| Hispanic | 77 (7) |
| other | 16 (3) |
| Premorbid renal function | |
| serum creatinine (mg/dl) | 1.1 ± 0.4 |
| eGFR (ml/min per 1.73 m2)a | |
| ≥60 | 686 (61) |
| 45 to 59 | 237 (21) |
| 30 to 44 | 124 (11) |
| Etiology of AKI | |
| ischemic | 871 (77) |
| nephrotoxic | 286 (25) |
| multifactorial | 626 (56) |
| Postsurgery | 463 (41) |
| Sepsis | 579 (52) |
| Mechanical ventilation | 905 (81) |
| Oliguria | 877 (78) |
| SOFA score | |
| respiratory | 2.3 ± 1.1 |
| coagulation | 1.4 ± 1.2 |
| liver | 1.4 ± 1.3 |
| cardiovascular | 2.3 ± 1.7 |
| central nervous system | 2.5 ± 1.4 |
| totalb | 13.8 ± 3.9 |
| Cleveland Clinic Score | 12.1 ± 3.4 |
| APACHE II | 26.4 ± 7.3 |
Continuous data are presented as mean ± SD, and categorical data as number of patients (%). eGFR, estimated glomerular filtration rate; SOFA, Sequential Organ Failure Assessment; APACHE II, Acute Physiology and Chronic Health Evaluation; AKI, acute kidney injury; BUN, blood urea nitrogen.
a
eGFR was calculated using four-variable MDRD estimation equation.
b
All patients assigned score of 4 for renal component of SOFA score.