Table 1.
Demographic characteristics of SCARB1 genotyped participants in the study sample (Mean ± SD or Number (Percent)) and nominal P-value from ANOVA.
African American | Chinese | European American | Hispanic | P-value | |
---|---|---|---|---|---|
Number of subjects | 711 | 630 | 712 | 704 | |
Females (%) | 391 (55.0%) | 335 (53.2%) | 380 (53.4%) | 381 (54.1%) | 0.90 |
Age (yr) | 61.5 ± 9.9 | 62.4 ± 10.4 | 61.5 ± 10.4 | 61.1 ± 10.1 | 0.20 |
BMI (kg/m2) | 30.1 ± 5.8 | 23.9 ± 3.3 | 27.8 ± 5.3 | 29.5 ± 5.1 | <0.0001 |
Waist Circ. (cm) | 101.0 ± 14.5 | 86.9 ± 10.0 | 97.8 ± 15.1 | 100.4 ± 12.8 | <0.0001 |
Glucose (mmol/L) | 5.9 ± 1.8 | 5.9 ± 1.5 | 5.4 ± 1.1 | 6.1 ± 2.2 | <0.0001 |
Hypertension | 397 (55.8%) | 231 (36.7%) | 277 (38.9%) | 295 (41.9%) | <0.001 |
Lipid Levels | |||||
HDL-C (mmol/L) | 1.4 ± 0.4 | 1.3 ± 0.3 | 1.4 ± 0.4 | 1.2 ± 0.3 | <0.0001 |
LDL-C (mmol/L) | 3.0 ± 0.9 | 3.0 ± 0.7 | 3.0 ± 0.8 | 3.1 ± 0.8 | 0.04 |
Total Cholesterol (mmol/L) | 4.9 ± 1.0 | 5.0 ± 0.8 | 5.1 ± 0.9 | 5.2 ± 1.0 | <0.0001 |
Triglycerides (mmol/L) | 1.2 ± 0.7 | 1.6 ± 1.0 | 1.5 ± 0.9 | 1.8 ± 1.3 | <0.0001 |
SCA | |||||
CCIMT (mm) | 0.91 ± 0.19 | 0.82 ± 0.17 | 0.87 ± 0.21 | 0.86 ± 0.18 | <0.0001 |
ICIMT (mm) | 1.10 ± 0.61 | 0.88 ± 0.48 | 1.09 ± 0.59 | 1.01 ± 0.56 | <0.0001 |
CAC present (%) | 300 (42.2%) | 311 (49.4%) | 393 (55.2%) | 316 (44.9%) | <0.001 |
To convert glucose to mg/dl divide by 0.0555; to convert cholesterol to mg/dl divide by 0.0259; to convert TG to mg/dl divide by 0.0113