Table 2.

Genotypic means by CCIMT (in mm) and linear regression coefficients (Betas) and empirical P-values for the association of SCARB1 SNP rs10846744 and CCIMT by racial/ethnic group under multiple models of adjustment. Model 1 includes adjustment for age, sex, and MESA center, while model 2 includes adjustment for these covariates, and also lipid levels (HDL-C, LDL-C, TC, and TG) and other major CVD risk factors (BMI, serum glucose, and HTN).

		CCIMT by Genotype (mm ± SD)			Model 1		Model 2
Racial/Ethnic Group	Minor Allele (Frequency)	C/C	G/C	G/G	Beta	P- value	Beta	P-value
African American	G (0.40)	0.92 ± 0.20	0.92 ± 0.19	0.87 ± 0.17	−0.022	0.02	−0.021	0.03
Chinese	G (0.42)	0.84 ± 0.19	0.82 ± 0.16	0.81 ± 0.16	−0.019	0.03	−0.020	0.02
European American	C (0.35)	0.90 ± 0.17	0.88 ± 0.21	0.86 ± 0.21	0.019	0.10	0.023	0.05
Hispanic	C (0.18)	0.89 ± 0.19	0.86 ± 0.19	0.83 ± 0.17	0.025	0.003	0.019	0.03