Figure 2. Metabolic assessment of Rip-Cre Tsc1 f/f and Rip-Cre Tsc1f/f, Tsc2 f/f. Random glucose (A) and insulin (B) levels obtained in the same group and age of mice. Intraperitoneal glucose tolerance tests (IPGTT) (C) were performed on the same group of mice. Measurements were performed on overnight -fasted 5–7 mo-old male control mice or Tsc 1f/f or Tsc1 f/f, Tsc2 f/f mice. Data are presented as mean SEM (n > 3). *p< 0.05 when compared with Rip-Cre Tsc1 f/f (solid gray line), Rip-Cre Tsc1 f/f Tsc2 f/f (dotted line) and control (solid black line).