Table 2.
Cardiovascular, urinary and metabolic variables
| All patients | Before fluid challenge | |||||
|---|---|---|---|---|---|---|
| Before fluid challenge | After fluid challenge | p | Non-responders | Responders | p | |
| Heart rate (beat.min-1) |
81 ± 19 | 77 ± 17 | 0.08 | 78 ± 14 | 83 ± 21 | 0.43 |
| Mean arterial pressure (mmHg) | 57 (53-59) | 67 (63-74) | < 0.001 | 56 (53-58) | 59 (53-60) | 0.45 |
| Central venous pressure (mmHg) | 8 ± 5 | 11 ± 6 | < 0.001 | 5 (4-10) | 9 (5-11) | 0.31 |
| Central venous saturation (%) | 72 ± 10 | 73 ± 10 | 0.22 | 73 ± 8 | 71 ± 11 | 0.45 |
| Arterial lactate (mMol.l-1) | 1.3 (1-2.1) | 1.3 (1-1.7) | 0.022 | 1.5 (0.8-2.5) | 1.3 (1-1.9) | 1 |
| Δv-aPCO2 (mmHg) |
6 (3.5-7.5) | 5(2.8-6.3) | 0.58 | 6 ± 3 | 5 ± 4 | 0.42 |
| Urinary output (ml.kg-1.h-1) | 0.7 (0.4-1.2) | 1.1 (0.6-1.6) | 0.024 | 0.7 (0.4-1.2) | 0.8 (0.4-1.1) | 0.53 |
| FENa (%) |
0.3 (0.1-1.2) | 0.4 (0.1-1.5) | 1 | 0.3 (0.1-1.3) | 0.4 (0.1-1.2) | 0.77 |
| Urinary Na/K ratio | 0.9 (0.3-2.2) | 0.8 (0.3-2.7) | 0.48 | 0.6 (0.2-2.5) | 1.1 (0.4-2.1) | 0.54 |
Δv-aPCO2: central venous to arterial CO2 partial pressure difference; FENa: fractional excretion of sodium. Data are shown as mean ± SD or median (interquartile range). Δv-aPCO2 and FENa were evaluated in 35 patients, urinary Na/K ratio 31 patients