Table 7.
Functional classification of cell cycle-regulated genes in both strainsa
| Strain | NRRL2338 | Px | ||
|---|---|---|---|---|
| COG | Functional categories | % COG probesets | % Probesets with q-value < = 0.001 | % Probesets with q-value < = 0.001 |
| I | Cellular processes and signaling | |||
| I.1 | Cell cycle control, cell division, chromosome partitioning | 0,35 | 0,99 | 0,69 |
| I.2 | Cell motility | 0,01 | 0 | 0 |
| I.3 | Cell wall/membrane/envelope biogenesis | 2,05 | 3,22 | 3,81 |
| I.4 | Defense mechanisms | 0,89 | 0,00 | 0,87 |
| I.5 | Intracellular trafficking, secretion, and vesicular transport | 0,24 | 0,25 | 0,69 |
| I.6 | Posttranslational modification, protein turnover, chaperones | 1,90 | 5,94 | 3,99 |
| I.7 | Signal transduction mechanisms | 1,91 | 0,99 | 1,91 |
| II | Information storage and processing | |||
| II.1 | Amino acid transport and metabolism | 0,01 | 0 | 0 |
| II.2 | Cell wall/membrane/envelope biogenesis | 0,01 | 0 | 0 |
| II.3 | Chromatin structure and dynamics | 0,01 | 0 | 0 |
| II.4 | General function prediction only | 0,30 | 0,50 | 0,35 |
| II.5 | Nucleotide transport and metabolism | 0,07 | 0 | 0 |
| II.6 | Posttranslational modification, protein turnover, chaperone | 0,04 | 0 | 0 |
| II.7 | Replication, recombination and repair | 2,44 | 0,74 | 2,43 |
| II.8 | RNA processing and modification | 0,01 | 0 | |
| II.9 | Secondary metabolites biosynthesis, transport catabolism | 0,04 | 0 | |
| II.10 | Signal transduction mechanisms | 0,71 | 0,50 | 0,69 |
| II.11 | Transcription | 7,20 | 2,23 | 3,29 |
| II.12 | Translation, ribosomal structure and biogenesis | 2,48 | 4,21 | 10,75 |
| III | Metabolism | |||
| III.l | Amino acid transport and metabolism | 6,60 | 0 | 8,15 |
| III.2 | Carbohydrate transport and metabolism | 6,08 | 7,67 | 6,59 |
| III.3 | Cell wall/membrane/envelope biogenesis | 0,38 | 0 | 0,17 |
| III.4 | Coenzyme transport and metabolism | 2,63 | 5,20 | 4,33 |
| III.5 | Energy production and conversion | 4,79 | 9,90 | 8,15 |
| III.6 | Inorganic ion transport and metabolism | 2,68 | 4,21 | 2,25 |
| III.7 | Lipid transport and metabolism | 4,24 | 2,72 | 5,03 |
| III.8 | Nucleotide transport and metabolism | 1,27 | 2,97 | 3,64 |
| III.9 | Posttranslational modification, protein turnover, chaperones | 0,08 | 0 | 0,17 |
| III.10 | Secondary metabolites biosynthesis, transport catabolism | 2,90 | 2,48 | 2,77 |
| III. 11 | Signal transduction mechanisms | 0,16 | 0 | 0 |
| IV | Poorly characterized | |||
| IV.1 | Function unknown | 32,11 | 27,23 | 22,70 |
| IV.2 | General function prediction only | 7,37 | 8,17 | 6,59 |
| Total probesets | 7060 | 404 | 577 | |
aThe categories over-represented and under-represented are evidenced, respectively, by BOLD and oblique number