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. 2012 Apr 12;5:10. doi: 10.1186/1755-8794-5-10

Table 1.

Correlation of mechanism-based candidate gene expression levels with birth weight

Gene Symbol Transcript ID HumanHT-12 v3 Expression
vs. Birth Weight % (R2)
Real Time RT-PCR Expression
vs. Birth Weight % (R2)
Cord Blood
(n = 48)
Placenta
(n = 48)
Cord Blood Placenta
IGF1 ILMN_2056087 2.0E-04 0.017 nd nd
ILMN_1709613 0.003 0.002
IGF1R ILMN_1675048 0.009 0.045 nd nd
IGF2 ILMN_1699867 1.3E-05 0.004 1.2E-04 (n = 190) 4.5E-04 (n = 254)
ILMN_2298035 0.008 0.001
ILMN_2413956 0.003 0.003
IGF2BP1 ILMN_1733807 0.007 1.0E-04 nd nd
IGF2BP2 ILMN_1702447 0.003 0.016 0.022 (n = 119) 1.0E-07 (n = 114)
IGF2BP3 ILMN_1807423 0.056 0.007 nd nd
IGF2R ILMN_1807662 0.006 3.0E-04 0.005 (n = 194) 6.1E-04 (n = 241)
IGFBP1 ILMN_2387385 0.014 0.001 ne 0.052 (n = 150)
ILMN_1728445 0.001 0.001
IGFBP2 ILMN_1725193 0.006 0.031 ne 0.003 (n = 110)
IGFBP3 ILMN_1746085 0.007 0.002 ne 0.001 (n = 135)
ILMN_2396875 0.009 0.002
IGFBP4 ILMN_1665865 0.006 0.003 nd nd
IGFBP5 ILMN_2132982 0.014 0.002 nd nd
ILMN_1750324 0.001 0.003
IGFBP6 ILMN_1669362 0.001 0.009 nd nd
IGFBP7 ILMN_2062468 2.5E-05 0.005 nd nd
INS ILMN_1666966 0.022 0.034 nd nd
INSR ILMN_1670918 0.058 0.031 nd nd
INSRR ILMN_1715374 0.007 3.9E-05 nd nd
PHLDA2 ILMN_1671557 0.036 0.001 nd nd
PLAGL1 ILMN_1815121 0.001 0.009 0.006 (n = 105) 0.013 (n = 136)
ILMN_2356955 0.014 0.004
IGF2/IGF2R* n/a n/a 0.002 (n = 186) 0.002 (n = 241)

Multiple entries represent data for multiple transcripts on the array. The best correlation obtained in each group is shown in bold

* Ratio IGF2/IGF2R expression

n/a = not applicable

nd = not done

ne = not expressed

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