Table 7.
ASTRO APBI consensus statement categories and classification criteria
| Criteria | Suitable | Cautionary | Unsuitable |
|---|---|---|---|
| Age | ≥ 60 | 50-59 | < 50 |
| Tumor Size | ≤ 2 cm | 2-3 cm | > 3 cm |
| T Stage | T1 | Tis and T2 | T3-T4 |
| Nodal biopsy | Yes | - | No |
| Margins | Negative (≥ 2 mm) | Close (< 2 mm) | Positive |
| Histology | Invasive ductal or other favorable subtypes | Invasive Lobular | - |
| Pure DCIS | No | ≤ 3 cm | > 3 cm |
| ER Receptor | Positive | Negative | - |
| LVSI* | No | Limited/Focal | Extensive |
| EIC* | No | ≤ 3 cm | > 3 cm |
* Presence of LVSI and EIC were considered cautionary in this study. Multicentricity, multifocality, neoadjuvant chemo/endocrine therapy, and known BRCA1/2 mutations were not present in any patients in this study. Pathologic nodal stage was pN0 for all patients who underwent axillary assessment