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Kaplan-Meier curves for time to first secondary events after samples taken: A & B subjects without diabetes, A time without acute MI, B time without admission to hospital with heart failure; C & D subjects with diabetes, C time without acute MI, D time without admission to hospital with heart failure. Quintiles (based on whole population) of gender-adjusted plasma betaine concentrations. Significance based on log-rank statistic for paired comparisons.
