Table 4.
Predicted equilibrium parasite densities required to maintain a positive RDT test
| Product | Min. detectable PfHRP2 conc. (ng/mL) | Est. no. parasites for MinCM (parasites/μL) | Est. no. parasites for MaxCM (parasites/μL) |
|---|---|---|---|
| Firstsign™ - ParaView (Pan + Pf) Malaria Test | 27.75 | 64.9 | 29.6 |
| SD BIOLINE Malaria Ag Pf/Pv | 6.94 | 16.7 | 7.8 |
| Carestart™ Malaria HRP2/pLDH | 6.94 | 16.7 | 7.8 |
| ICT Malaria Combo Cassette Test | 13.88* | 32.8 | 15.1 |
* The lowest dilution which gives a band intensity > 1 to adjust for false positive result on negative control.
MinCM and MaxCM represent the minimum circulating model and maximum circulating model, respectively.