Figure 4. The mean square distance of genomic loci to the center-of-mass of the chromosome territory (top, blue line) depends on the corresponding expression level [3] (gray): The lowly transcribed regions are closer to the center than more active parts of the fibre.

The mean square distance to the surface of the chromosome territory (bottom, blue line) confirms that the highly expressed loci preferentially reside closer to the surface of each territory than lowly expressed regions.