Table 1. Results of association study and joint analysis.
Number | SNP | Confirmation sample (n = 3245) | OR2 | L95 | U95 | HWEp3 | Confirmation sample + JGWAS (n = 4353) | ||||||
Cases | Controls | P-value1 | P-value1 | OR2 | L95 | U95 | P_BD4 | ||||||
1 | rs2190665 | 0.39 | 0.42 | 0.06 | 0.91 | 0.82 | 1.01 | 0.79 | 0.0033 | 0.88 | 0.80 | 0.96 | 0.22 |
2 | rs10260177 | 0.04 | 0.04 | 0.39 | 1.12 | 0.87 | 1.44 | 0.49 | 0.44 | 0.92 | 0.74 | 1.14 | 0.003 |
3 | rs2215379 | 0.21 | 0.21 | 0.85 | 1.01 | 0.89 | 1.15 | 0.88 | 0.18 | 0.93 | 0.84 | 1.03 | 0.01 |
4 | rs4729938 | 0.32 | 0.31 | 0.33 | 1.06 | 0.95 | 1.18 | 0.72 | 0.027 | 1.11 | 1.01 | 1.22 | 0.08 |
Fisher’s exact test.
Odds ratio.
Hardy–Weinberg equilibrium p-value in controls.
Breslow-Day test p-value.