Table 2. Association between Three M. tuberculosis Strain Lineages and Isoniazid-Resistance Conferring Mutations.
| East-Asian Lineage | Euro-American | Indo-Oceanic | Other lineages | Odds Ratio | P-value | |
| Mutation, n (%) | (n = 17) | (n = 44) | (n = 36) | (n = 4) | (95% CI)a | |
| (1) katG other than S315T | 6 (35.3) | 8 (18.2) | 5 (13.9) | 0 (0) | 2.98 (0.94–9.48) | 0.064 |
| (2) katG S315T | 4 (23.5) | 18 (40.9) | 14 (38.9) | 2 (50.0) | 1.28 (0.57–2.88) | 0.55 |
| (3) inhA-15;c-t promoter | 4 (23.5) | 9 (20.5) | 14 (38.9) | 2 (50.0) | 2.12 (0.88–5.14) | 0.096 |
| (4) Other or none identified | 3 (17.6) | 9 (20.5) | 3 (8.3) | 0 (0) | 2.19 (0.71–6.69) | 0.171 |
a
For each lineage, logistic regression was used to compare the proportion of the most frequent mutation to its proportion in the other lineages combined.