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. 2012 May 23;7(5):e37956. doi: 10.1371/journal.pone.0037956

Table 4. Association Between Isoniazid (INH) Resistance-conferring Mutations and High-Level INH Resistance.

Mutation Group Total Cases High-Level INH Resistance Association with High-Level INH Resistance P-value
n (%) Adjusted Risk Ratio (95% CI)a
(1) katG other than S315T 19 12 (63) reference
(2) katG S315T 38 35 (92) 1.56 (1.07–2.27) 0.02
(3) inhA-15;c-t promoter 29 7 (24) 0.43 (0.21–0.89) 0.02
(4) Other or none identified 15 9 (60) 1.01 (0.62–1.64) 0.98
a

Poisson regression with robust error variance was used to measure association between INH resistance-conferring mutation group and high-level INH resistance.