Table 1.

A. Multivariable Model for Mortality (Total N=549, 178 deaths)
	Hazard Ratio	95% CI	P-value	Reliability
Early Phase
OPVR vs. No OPVR	4.75	(2.65, 8.52)	<.001	88%
No HLHS vs. HLHS with AS/MS	4.00	(1.91, 8.37)	<.001
No HLHS vs. HLHS with AA/MS	1.75	(0.98, 3.13)	.06
No HLHS vs. HLHS with AS/MA	1.28	(0.46, 1.56)	.63
No HLHS vs. HLHS with AA/MA	2.07	(1.12, 3.82)	.021
Lower SES score (per 5-point decrease)	1.28	(1.06, 1.56)	.012	64%
Smaller ascending aorta diameter, per mm	1.23	(1.04, 1.45)	.013	63%
RVPAS vs. MBTS				56%, 55%
Term, Aortic valve not patent	0.36	(0.22, 0.60)	<.001
Term, Aortic valve patent	0.57	(0.49, 1.47)	.52
Preterm, Aortic valve not patent	1.25	(0.66, 2.38)	.49
Preterm, Aortic valve patent	2.97	(1.43, 6.19)	.004
Constant Phase
Lower Gestational age, per wk	1.56	(1.28, 1.90)	<.001	50%
Genetic syndrome present vs.	9.34	(3.07, 28.40)	<.001	55%
None
Genetic syndrome unknown vs.	4.74	(2.10, 10.72)	<.001	78%
None
RVPAS vs. MBTS*	1.10	(0.43, 2.83)	.85	78%

B. Additional Pairwise Anatomic Diagnosis Comparisons from Multivariable Model for Death in Table 1A.
Comparison		Hazard Ratio	95% CI	P-value
AS/MS vs.
AA/MA		0.52	(0.23, 1.15)	.11
AA/MS		0.44	(0.20, 0.95)	.04
AS/MA		0.32	(0.10, 1.00)	.05
AA/MA vs.
AA/MS		0.84	(0.54, 1.31)	.46
AS/MA		0.62	(0.23, 1.67)	.35
AA/MS vs. AS/MA		0.73	(0.27, 1.98)	.54

AA = aortic atresia; AS = aortic stenosis; HLHS = hypoplastic left heart syndrome; MA = mitral atresia; MBTS = modified Blalock-Taussig shunt; RVPAS = right ventricle-to-pulmonary-artery shunt; MS = mitral stenosis; OPVR = obstructed pulmonary venous return; SES = socioeconomic score

^**Shunt type forced into model

AA = aortic atresia; AS = aortic stenosis; MA = mitral atresia; MS = mitral stenosis