Table 1.
Demographic data of patients at time of transplantation. The P-value compares the two groups ESA and no-ESA therapy.
| Variable | No ESA therapy | ESA therapy | P-value |
|---|---|---|---|
| Number of patients | 758 | 683 | n. a. |
| Recipient sex (M/F) | 488/270 | 377/306 | <0.001 |
| Donor sex (M/F) | 444/287 | 387/276 | 0.368 |
| Renal Diagnosis (glomerulonephritis/vascular/diabetes/else) | 214/63/95/380 | 178/66/73/364 | 0.378 |
| Cause of death (cardvasc/infection/malign/else) | 70/33/25/28 | 69/51/14/41 | 0.039 |
| Diabetes mellitus (no/yes) | 644/114 | 570/113 | 0.434 |
| Number of Hypertensives (0/1/2/3/4/5/6/7) | 100/135/189/173/101/39/11/1 | 74/101/166/144/102/66/13/0 | 0.023 |
| BCAR (yes/no/unknown) | 342/307/43 | 369/213/19 | <0.001 |
| CMV (R-Dā/R-D+/R+D-/R+D+/unknown) | 65/113/116/248/216 | 53/106/113/231/180 | |
| Insulin (yes/no/unknown) | 89/666/1 | 95/447/1 | 0.014* |
| Immunosuppression (steroid + AZA + CsA/steroid ā+ MMF + CsA/no steroid/else and unknown) |
220/196/58/284 | 175/161/55/292 | 0.183 |
| CNI (no/yes) | 161/597 | 109/57 | 0.010 |
| CIT (h) | 17.8 (8.0) | 16.6 (8.5) | 0.009 |
| Donor age (years) | 40 (16) | 47 (15) | <0.001 |
| Weight (kg) | 71 (16) | 71 (16) | 0.493 |
| Sum of HLA mismatch | 2.5 (1.8) | 2.5 (1.4) | 0.648 |
| PRA | 4.5 (12.5) | 4.7 (12.6) | 0.774 |
| Recipient age (years) | 49 (15) | 49 (15) | 0.709 |
| GFR (ml/min/1.73 m2) | 46 (24) | 40 (24) | <0.001 |
| Creatinine (mg/dl) | 1.97 (1.36) | 2.27 (1.58) | <0.001 |
| Hemoglobin (g/l) | 11.4 (2.4) | 10.8 (2.6) | <0.001 |
*
Fisher exact test.
BCAR, biopsy confirmed acute rejection; CMV, cytomegalie virus; R, recipient; D, donor; CNI, calcineurin inhibitor; CIT, cold ischemic time; PRA, panel reactive antibody.