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The effect of inhibitors on the degradation of EMs by DPP IV
| Inhibitor | DPP IV | |||
|---|---|---|---|---|
| EM-1 | EM-2 | |||
| Inhibition (%) | K i (μM) | Inhibition (%) | K i (μM) | |
| Diprotin A | 96.8 ± 3.27 | 2.2a | 97.1 ± 4.00 | 2.2a |
| Tyr-Pro-Ala-NH2 (EMDB-2) | 26.7 ± 1.20 | 420 | 44.8 ± 2.51 | 170 |
| Tyr-Pro-Ala-OH (EMDB-3) | 39.1 ± 1.41 | 270 | 60.0 ± 2.27 | 100 |
aValue taken from Ref. Umezawa et al. (1984)
