Figure 1.

Selective autophagy and the corresponding organelle marker, receptor and adaptor proteins. The Atg11 interaction domain of Atg32 has not been mapped at present and the indicated position is approximate. (A) Key motifs of the marker and receptor proteins; (B) Atg8/LC3 interaction motifs of autophagic marker and receptor proteins; (C) Models of selective autophagy in different organisms. Atg32 shares properties of both organelle/cargo marker proteins and receptors; it is an integral membrane component of the mitochondria, and it binds both Atg11 and Atg8. TMD, transmembrane domain; UBA, ubiquitin-associated domain.